I am a Masters student, in the Faculty of Science in Canada. I have a question to ask regarding literature review. I am doing a bit of studying to find protocols for my experiment (where I hope to conjugate a certain linker to a nucleic acid). I tried looking for papers with different keyword searches on Google Scholar, as well as the WebOfScience.
There could be different possibilities here - either there is no papers that has been published, else the Search Spider was not able to find the papers (which is a False Result).
I, therefore tried looking for a paper which we had published 4-5 years back in Journal of Chemical and Pharmaceutical Research. It does not show up in the search results probably because it does not have enough citations (you can try by searching this paper on Google standard search, and on Google Scholar: Potential inhibitors against acetylcholinesterase and glutathione S-transferase associated with Alzheimer's disease).
Doesn't this give a false hope to certain researchers, that the work they are currently doing is novel; or make it difficult to other researchers who are trying to find a protocol to adopt?
Hoping to get some insight from the community.