From Nature's "Getting Published with Nature" guidelines:

Nature has space to publish only 8% or so of the 200 papers submitted each week, hence its selection criteria are rigorous. Many submissions are declined without being sent for review.

This leads me to the question:

Question: What proportion of the papers submitted to Nature actually get sent for review?

It'd be nice to know if, in general, the "biggest hurdle" in getting a paper published in Nature would be simply getting it to the reviewers.

  • Also, what are the reasons to reject a submission before reviewing?
    – seteropere
    Commented Mar 20, 2013 at 14:28
  • 8
    @seteropere that is a completely different question, which you should ask separately!
    – F'x
    Commented Mar 20, 2013 at 14:32
  • 1
    @seteropere: I can't speak for Nature, but this is ACM TISSEC's reviewing process, a top journal in computer security. Basically, it can be rejected before reviewing for being off-topic, or if the substance is wrong.
    – user102
    Commented Mar 20, 2013 at 14:32
  • 1
    Related, but does not directly answer your question: see this post by Philip Ball and the paper it is based on. (Also, this one)
    – F'x
    Commented Mar 20, 2013 at 14:35

2 Answers 2


Edited: I found a better answer to the question, the original indicative answer is left below.

Here, we have a statement from December 2006 regarding the number of submissions, rate of editor rejections and ultimate acceptance number. While slightly outdated, the acceptance rate of Nature journal does not seem to fluctuate widely between 2006 and 2012 (always around 7-8% of submitted articles), hence I believe the number is significant and valid:

Nature receives approximately 10,000 papers every year and our editors reject about 60% of them without review. ... ... In the end we publish about 7% of our submissions.

From that we have, that in 2006 about 40% of submissions were sent out for peer-review.

The original indicative answer:
Not a precise answer, but can be indicative also for Nature journal itself: here is a statistics of a decade 2002-2012 of publishing in Nature Materials in numbers, various stats are presented. Specifically this graph shows that the ratio of peer-reviewed vs. submitted manuscripts is floating around 13%. Out of peer-reviewed, about 60% get accepted. This shows that their first filter, the editorial decision whether to review at all, is extremely aggressive and in fact is the filter in the publishing process.

According to a note here, Nature Neuroscience sends about 30-35% papers for peer-review.

  • 1
    It would seem that the editor would have to be very familiar with you and the significance of your work ahead of time to get published in Nature.
    – Paul
    Commented Mar 20, 2013 at 17:29
  • @DouglasS.Stones: I found an answer for Nature journal itself. See my edited answer.
    – walkmanyi
    Commented Mar 21, 2013 at 8:06

These data are a bit more recent and specifically from Nature Microbiology, one of the newer NPG journals.

We sent out slightly over 20% of submitted manuscripts for review and our acceptance rate was 9%. Of those 126 manuscripts accepted, 86% were published after 2 rounds of review or fewer, while 14% needed to be seen by at least 1 referee a third time.

noting this, it looks like the largest of the hurdles is indeed getting sent out for peer review.

source: https://www.nature.com/articles/nmicrobiol2016259

  • 4
    I don't really think a non-Nature journal from NPG really gives much insight into Nature itself.
    – Bryan Krause
    Commented Sep 15, 2021 at 19:41

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