Yes. You have to be realistic, though. Making such a transition takes time, as you're starting from square one. It also can be financially challenging, as you progress through the education. You may not find a lot of choices at first, but with effort, you can begin to expand your horizons after building your academic reputation.
I suppose my answer is from personal experience.
Two years ago, I began to pursue a full, rich career in physics. My undergraduate degrees, though, were in business and psychology. I had virtually no experience outside of introductory collegiate physics and some calculus I had taken as an undergrad. My work experience did not exactly apply.
Not unexpectedly, the choices for a program were limited. I found a good State university nearby that accepted me conditionally to its Master's program. There are some other students at this school who have had other backgrounds as well - another I know well was an English major. Some of us started from scratch. As conditional students, we had to more-or-less complete the entire BS curriculum prior starting grad classes. That took about two years. Where I am now, it'll take about two more years for the Master's.
My partner is in the same boat, but with mathematics. She held a liberal arts degree. She was rejected for conditional admission, and so began to take classes to bolster her foundations. After a year of study, she reapplied and was accepted. Again, she is working towards her graduate degree after several semesters of fulfilling undergraduate level material.
I have observed others in the same situation successfully enter industry and PhD programs at all levels of prestige and interest. Regardless, those who excelled only did so through a lot of blood, sweat, and tears.
So, yes. It's a long road, but it can be traveled.