There was recently a talk at my university of someone who wrote the most cited paper in the top journal of my field. Something like that is usually easy to look up for a single journal, but it made me wonder which would be the most cited paper published in any scientific journal (conference proceedings also count) until now?
Nature put out a list recently of the most cited papers in Web of Science.
At the top, with more than 300k citations, was a methods paper:
Protein measurement with the folin phenol reagent. Lowry, O. H., Rosebrough, N. J., Farr, A. L. & Randall, R. J. J. Biol. Chem. 193, 265–275 (1951).