I am curious to hear some words of advice on how to select a publishing community for multi-disciplinary topics.
Your contribution is that methods in area A, which is your main area, can solve problems in B more efficiently than traditionally used methods from area C.
Where do you publish, A, B, or C? You are contributing a new application domain to your main area A, along with theory that supports the bridge between A and B, but your reviewers are not familiar with domain B and do not find it relevant. You are contributing new tools to the problem domain B. Finally, all of the related work is in C.
This is CS research, if that helps.