I don't care how important the journal is or who the editors are. The question is do I read it, or do the papers of relevance turn up in it, or do the most relevant/sympathetic authors publish in it, which means there will be relevant/sympathetic reviewers. Publish in the journals where you see the most similar papers to what you are proposing, in approach, scope, length, depth, etc. It is appropriate to publish short papers on new results quickly in the more specialised transactions, and longer papers that draw together work and provide introductions to a broader audience in the more general journals. If the work is interdisciplinary it is appropriate to present it for different audiences by retargeting to a new journal. The more ground breaking the research the more important it is rather to see what journals publish novel research as opposed to bandwagon research. If none of the reviewers understand it, a reputable venue will not publish it (although often they won't admit the problem is theirs).
But in general the story goes like this...
research --> journals that publish that research --> most appropriate journal for your research --> target that specific journal
In other words I think you have it backwards - you choose the venue and then target the paper to it. I develop repositories of knowledge for my own use (somewhere between a collection of notes and thesis-like treatise). Sometimes I publish these as a Tech.Report. but the idea is not to publish on the growing body of work, but to draw on it as it grows to target papers to particular venues (workshops, conferences, transactions and journals).
I regard general journals as the least useful kind of publication, and workshops as the most useful kind of publication, with a funnel type progression to a proper journal paper (which I my field are typically 50-100 page papers whereas the other three typically have 6-12 page papers). In the internet age, the most important thing is to publish in places that provide or allow open access, and most readers will come from a search process rather than by subscription to the journal. Subscription journals are dead - they just don't know it yet, although the publishers are scrambling to get you, your employer or oterh sponsors to continue to pay them in a paid open access model.