The overwhelming majority of journals that use the Chicago style allow you to include "asides" along with source material references. In fact it is quite a common thing. For an example of how references and extra comments can be mixed together into a single footnote, just read any article from Monumenta Nipponica, or JSAH.
Nevertheless, do be sure to double-check the specific requirements and instructions provided by the journal in question, and confirm if they have any problem with including general info in the footnotes.
EDIT: here is an example of several mixed references together with additional comments within a single note, taken from the following paper:
(Note that endnotes can be written in the same manner as footnotes, there is no difference except in their placement within the paper itself)