In short - wrote an article, sent the manuscript to all co-authors and asked for consent for submission and for feedback, if any. After most of the co-authors replied, I made some small tweaks to the manuscript that improved it, but I'm still waiting for consent from 2 co-authors. I sent the e-mail 2 weeks ago, and that should be enough time for them to at least acknowledge they received it, right? All other co-authors replied within a few days.
What makes this especially interesting is the fact that the 2 co-authors that didn't respond were the ones not actually super involved in the experiments, they just provided the transgenic model that I experimented on. I included them as authors on the first (published in a journal) paper because my PI told me we should include them because of that and ok. But now they aren't responding at all, so I'm wondering how to move forward. Remind them? When? Just submit without their consent? Remove them from the author block (and risk a clash with the PI)? I want to submit this, but have no idea what to do.