I worked in a research group and now I am applying to a PhD program. A positive reference letter, especially the one from the big-named Principal Investigator (PI, project leader), will be very helpful.
My direct supervisor was a Research Scientist instead of a professor (PI). The professor (PI) of our group knows me, but not very well, since he has dozens of Postdocs and dozens of students to take care of. So I am think about having my direct supervisor write the letter and having the PI to co-sign.
However I've heard that two people signing a single reference letter is extremely uncommon is US. Not sure what is my best option.