Specializing the question Who to address on the cover letter?, let's assume that you apply for a tenure-track position in the US in computer science, that the job announcement has no particular individual listed, and that Google/Bing/Yahoo led you to, say, "recruiting committee" (as opposed to "search team"). Then, which opening would be proper:
To Whom It May Concern
or
Dear Recruiting Committee
or
To the Recruiting Committee
or
Dear Representative of the Recruiting Committee
or
Dear Ladies and Gentlemen
?
How about the punctuation after the opening? No punctuation, a comma, or a colon? I.e.:
〈Whatever opening〉
〈Whatever opening〉,
〈Whatever opening〉:
All are o.k. according to the broad English grammar, but, in academia things might be more special.
Dear Search Committee,
for my US CS TT applications.yo’ doodz, pls gimme a job
. Your success is not gong to come down to the salutation on your cover letter. Also, yes, I’ve gotten several interviews thus far. Thank you for asking and good luck to you.